Publications

Axente M, He J, Bass CP, Hirsch JI, Sundaresan G , Zweit J, and Pugachev A. (2011) Comprehensive approach to co-registration of autoradiography and microscopy images acquired from a set of sequential tissue sections.  Journal of Nuclear Medicine, 52(10): 1621-9.

Sun M, Hoffman D, Sundaresan G, Yang L, Lamichhane N, Zweit J (2012). Synthesis and characterization of intrinsically radio-labeled quantum dots for bimodel detection. American Journal of Nuclear Medicine and Molecular Imaging, 2(2): 122-135.

Weibo C, Hao H (2012). In a “nutshell”: intrinsically radio-labeled quantum dots. American Journal of Nuclear Medicine and Molecular Imaging, 2(2):136-140.

Axente M, He J, Bass C, Hirsch J, Gobalakrishnan S, Williamson J, Zweit J, Pugachev A. (2012) Tumour microenvironment heterogeneity affects the perceived spatial concordance between the intratumoural patterns of cell proliferation and 18F-fluorothymidine uptake. Radiotherapy and Oncology  (in press).

Dewkar G, Gobalakrishnan S, Lamichhane N, Hirsch J, Thadigiri C, Youniss F, Collier T, Hartman M, Vaidyanthan G, Zweit J. (2012). Improved radiosynthesis and in vivo evaluation of [18F] 2-(5-fluoro-pentyl)-2-methyl malonic acid. Journal of Labeled Compounds and Radiopharmaceuticals (submitted).

2007

Shaw DM, Connolly NB, Patel PM, Kilany S, Hedlund G, Nordle Ö, Forsberg G, Zweit J, Stern PL, Hawkins RE. A phase II study of a 5T4 oncofetal antigen tumor-targeted superantigen (ABR- 214936) therapy in patients with advanced renal cell carcinoma. British Journal of Cancer. 2007. 96:567-574.

Kalen JD, Hirsch JI, Kurdziel K, Eckelman WC, Kiesewetter DO. Automated Synthesis of 18F Analogue of Paclitaxel (PAC): [18F] Paclitaxel (FPAC). Applied Radiation and Isotopes. 2007. 65(6):696-700.

Kurdziel KA, Kalen JD, Hirsch JI, Wilson JD, Rakesh A, Barrett D, Bear HD, McCumiskey JF. Imaging Multidrug Resistance with 4-[18F] Fluoropaclitaxel. Nuclear Medicine and Biology. 2007. 34(7):823-831.

2006

Gillies JM, Prenant C, Chimon GN, Smethurst GJ, Perrie W, Hamblett I, Dekker B, Zweit J. A Microfluidic Reactor for the Radiosynthesis of PET Radiotracers. Applied Radiation and Isotopes. 2006. 64:325-332.

Gillies JM, Najim N, Zweit J. Analysis of metal radioisotope impurities generated in [18O]H2O during the production of fluorine-18. Applied Radiation and Isotopes. 2006.64:431-434.

Gillies JM, Smethurst GJ, Hamblett I, Dekker B, Chimon GN, Prenant C, Zweit J. Microfluidic technology for PET radiochemistry. Applied Radiation and Isotopes. 2006. 64:333-336.

Workman P, Aboagye E, Chung YL, Griffiths J, Hart R, Leach M, Maxwell R, McSheehy P, Price P, Zweit J. For the Cancer Research UK Pharmacodynamic/Pharmacokinetic Technologies Advisory Committee. Minimally Invasive Pharmacokinetic and Pharmacodynamic Technologies in Hypothesis-testing Clinical Trials of Innovative Therapies. Journal of the National Cancer Institute. 2006. 98:580-598.

Williams H, Zweit J, Gillies J, Julyan P, Hastings D, Ransom M. Does 124Iodo-deoxyuridine measure cell proliferation in NSCLC? Initial investigations with PET imaging and radio-metabolite analysis. European Journal of Nuclear Medicine and Molecular Imaging. 2006. 34:301-303.

Kurdziel K, Hirsch J, Kalen J, Wilson J. Human Biodistribution of F-18 Paclitaxel (FPAC): A Potential PET Tracer for Evaluating Multidrug Resistance (MDR). Molecular Imaging and Biology. 2006. 8(2):72.

Wilson J, Kalen J, Hirsch J, Agarwal R, Barrett D, Kurdziel K. Evaluation of [F-18] Paclitaxel (FPAC) as a Positron Emission Tomography Tracer for Pgp Expression in Cells and in Human Epithelial Tumor Mouse Xenografts. Molecular Imaging and Biology. 2006. 8(2):74.

2005

Harris ML, Julyan P, Kulkarni B, Gow D, Hobson A, Hastings D, Zweit J, Hamdy S. Mapping metabolic brain activation during human volitonal swallowing: A positron emission tomography study using [F-18]fluorodeoxy glucose. Journal of Cerebral Blood Flow and Metabolism. 2005. 25:520-526.

Jayson GC, Mulatero C, Ranson M, Zweit J, Jackson A, Broughton L, Wagstaff  J, Hakannson L, Groenewegen G, Lawrance J, Tang M, Wauk L, Levitt D, Marreaud D, Lehmann FF, Herold M, Zwierzina H. Phase I investigation of recombinant anti-human vascular endothelial growth factor antibody in patients with advanced cancer. European Journal of Cancer. 2005. 41:555.

Williams H, Robinson S, Julyan P, Zweit J, Hastings D. A comparison of PET imaging characteristics of various copper radioisotopes. European Journal of Nuclear Medicine and Molecular Imaging. 2005. 32:1473-1480.

Dekker BA, Keen HG, Shaw D, Disley L, Hastings D, Hadfield J, Reader A, Allan D, Julyan P, Watson A, Zweit J. Functional comparison of annexin V analogues labeled indirectly and directly with iodine-124. Nuclear Medicine and Biology. 2005. 32:403-413.

Dekker BA, Keen HG, Lyons S, Disley L, Hastings H, Reader AJ, Ottewell P, Watson A, Zweit J. MBP–annexin V radiolabeled directly with iodine-124 can be used to image apoptosis in vivo using PET. Nuclear Medicine and Biology. 2005. 32:241-252.

Keen HG, Dekker BA, Disley L, Hastings H, Lyons S, Reader AJ, Ottewell P, Watson A, Zweit J. Imaging apoptosis in vivo using 124I-annexin V and PET. Nuclear Medicine and Biology. 2005. 32:395-402.

2004

Ledingham KWD, McKenna P, McCanny T, Shimizu S, Yang J, Robson L, Zweit J, Gillies JM, Bailey J, Chimon GN, Singhal RP, Wei MS, Mangles S, Nick elson P, Krushelnick K, Zepf M, Clarke RJ, Norreys PA. High-powered laser production of short lived isotopes for positron emission tomography. Journal of Physics D: Applied Physics. 2004. 37:2341.

Robinson S, Julyan PJ, Hastings DL, Zweit J. Performance of a block detector PET scanner in imaging non-pure positron emitters — modelling and experimental validation with 124I. Physics in Medicine and Biology. 2004. 49:5505-5528.

Ledingham KWD, McKenna P, McCanny T, Shimizu S, Yang J, Robson L, Zweit J, Gillies JM, Bailey J, Chimon GN, Singhal RP, Wei MS, Mangles S, Nickelson P, Krushelnick K, Zepf M, Clarke RJ, Norreys PA. Laser-produced radioactive isotopes. Editors choice, Science. 2004. 305:921.

Harris et. al. Mapping Metabolic Brain Activation During Human Volitional Swallowing: A Positron Emission Tomography (PET) Study Using [18F] Fluorodeoxyglucose. Journal of Cerebral Blood Flow and Metabolism. 2004. 25:520-526.

Hirsch JI, Kalen JD, Kiesewetter DO, Kurdziel KA, Eckelman WC. Automated Synthesis of 18F Analogue of Paclitaxel (PAC):[18F] Paclitaxel (FPAC). Journal of Nuclear Medicine. 2004.

2003

Reader AJ, Julyan PJ, Williams H, Hastings DL, Zweit J. EM Algorithm System Modeling by Image-Space Techniques for PET reconstruction. IEEE T. Nucl. Sci. 2003. 50:1392-1397.

Kanu AB, Dixon M, Zu YY, Bailey J, Gillies JM, Zweit J, Thomas CLP. Rapid screening of 2-[18F]-fluoro-2-deoxy-D-glucose infusions for volatile organic compound contaminants by solid phase microextraction with gas chromatography – selective ion monitoring mass spectrometry. Applied Radiation and Isotopes. 2003. 58:193-200.

2002

Reader AJ, Ally S, Bakatselos F, Manavaki R, Walledge RJ, Jeavons AP, Julyan PJ, Zhao S, Hastings DL, Zweit J. One-Pass List-Mode EM Algorithm for High Resolution 3D PET Image Reconstruction Into Large Arrays. IEEE T. Nucl. Sci. 2002. 49:693-699.

Walledge RJ, Manavaki R, Reader AJ, Jeavons AP, Julyan PJ, Hastings DL, Zweit J. Quad-HIDAC PET: Comparison of List-Mode and Projection-Data Driven Image Reconstruction for High Resolution Imaging. IEEE T. Nucl. Sci. 2002.

Jayson GC, Zweit J, Jackson A, Mulatero C, Julyan P, Ranson M, Broughton L, Wagstaff J, Hakannson L, Groenewegen G, Bailey J, Smith N, Hastings D, Lawrance J, Haroon H, Ward T, McGown AT, Tang T, Levitt D, Marreaud S, Lehmann FF, Herold M, Zwierzina H. Molecular imaging and biological evaluation of HuMV833 anti-VEGF antibody: Implications for trial design of anti-angiogenic antibodies. Journal of the National Cancer Institute. 2002. 94:1484-1493.

Reader AJ, Manavaki R, Zhao S, Julyan PJ, Hastings DL, Zweit J. Accelerated List-Mode EM Algorithm. IEEE T. Nucl. Sci. 2002. 49:42-49.

2001

Burke D, Davies MM, Zweit J, Flower MA, Ott RJ, Dworkin MJ, Glover C, McCready VR, Carnochan P, Allen-Mersh TG. Continuous angiotensin II infusion increases tumour: normal blood flow ratio in colorectal liver metastases. British Journal of Cancer. 2001. 85:1640-1645.

Lee FT, Hall C, Rigopoulos A, Zweit J, Pathmaraj K, O’Keefe GJ, Smyth FE, Welt S, Old LJ, Scott AM. ImmunoPET of human colon xenograft-bearing balb/c nude mice using I-124-CDR-grafted humanised A33 monoclonal antibody. Journal of Nuclear Medicine. 2001. 42:764-760.

Flower M, Zweit J, Hall A, Burke D, Davies M, Dworkin M, Young H, Mundy J, Ott R, McReady R, Carnochan P, Allen-Mersh T. Cu-62-PTSM and PET used for the assessment of angiotensinII-induced blood flow changes in patients with colorectal liver metastases. European Journal of Nuclear Medicine. 2001. 28:99-103.

Reader AJ, Zhao S, Julyan PJ, Hastings DL and Zweit J. Adaptive Correction of Scatter and Random Events for 3D Backprojected PET Data. IEEE T. Nucl. Sci. 2001. 48:1350-1356

Reader AJ and Zweit J. Developments in whole body molecular imaging of live subjects. Trends in Pharmacological Sciences. 2001. 22:604-607.

Towu E, Boxer G, Begent R, Zweit J, Spitz L, Hobbs K, Winslet M. In-vitro uptake of radioactive lipiodol I131 and I-125 by hepatoblastoma: Implications for targeted radiotherapy. Pediatric Surgery International. 2001. 17:609- 613.

Duraisamy Y, Slevin M, Smith N, Bailey J, Zweit J, Smith C, Ahmed N, Gaffney J. Effect of glycation on basic fibroblast growth factor induced angiogenesis and activation of associated signal transduction pathways in vascular endothelial cells: Possible relevance to wound healing in diabetes. Angiogenesis. 2001. 4:277-288.